mitf isoform m mitf m Search Results


mitf-m protein  (ESUMI Co Ltd)
90
ESUMI Co Ltd mitf-m protein
DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the <t>cAMP-CREB-MITF</t> cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.
Mitf M Protein, supplied by ESUMI Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mitf+isoform+m+mitf+m/pmc06336527-78-5-43?v=ESUMI+Co+Ltd
Average 90 stars, based on 1 article reviews
mitf-m protein - by Bioz Stars, 2026-08
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gene exp mitf hs01117294 m1  (Thermo Fisher)
95
Thermo Fisher gene exp mitf hs01117294 m1
DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the <t>cAMP-CREB-MITF</t> cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.
Gene Exp Mitf Hs01117294 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mitf+isoform+m+mitf+m/ppr0039567-98-26-14?v=Thermo+Fisher
Average 95 stars, based on 1 article reviews
gene exp mitf hs01117294 m1 - by Bioz Stars, 2026-08
95/100 stars
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gene exp ipo8 hs00183533 m1  (Thermo Fisher)
99
Thermo Fisher gene exp ipo8 hs00183533 m1
DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the <t>cAMP-CREB-MITF</t> cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.
Gene Exp Ipo8 Hs00183533 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mitf+isoform+m+mitf+m/ppr0039567-98-36-14?v=Thermo+Fisher
Average 99 stars, based on 1 article reviews
gene exp ipo8 hs00183533 m1 - by Bioz Stars, 2026-08
99/100 stars
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gene exp cited1 hs00918445 g1  (Thermo Fisher)
86
Thermo Fisher gene exp cited1 hs00918445 g1
DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the <t>cAMP-CREB-MITF</t> cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.
Gene Exp Cited1 Hs00918445 G1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mitf+isoform+m+mitf+m/ppr0096738-92-33-14?v=Thermo+Fisher
Average 86 stars, based on 1 article reviews
gene exp cited1 hs00918445 g1 - by Bioz Stars, 2026-08
86/100 stars
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rt-pcr  (StemCells Inc)
90
StemCells Inc rt-pcr
DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the <t>cAMP-CREB-MITF</t> cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.
Rt Pcr, supplied by StemCells Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mitf+isoform+m+mitf+m/pm16574754-171-30-51?v=StemCells+Inc
Average 90 stars, based on 1 article reviews
rt-pcr - by Bioz Stars, 2026-08
90/100 stars
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vectastain elite abc hrp kit (peroxidase, standard)  (Vector Laboratories)
99
Vector Laboratories vectastain elite abc hrp kit (peroxidase, standard)
DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the <t>cAMP-CREB-MITF</t> cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.
Vectastain Elite Abc Hrp Kit (Peroxidase, Standard), supplied by Vector Laboratories, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mitf+isoform+m+mitf+m/custom%40pk-6100%4026168401?v=Vector+Laboratories
Average 99 stars, based on 1 article reviews
vectastain elite abc hrp kit (peroxidase, standard) - by Bioz Stars, 2026-08
99/100 stars
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microphthalmia transcription factor  (Selzer GmbH)
90
Selzer GmbH microphthalmia transcription factor
DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the <t>cAMP-CREB-MITF</t> cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.
Microphthalmia Transcription Factor, supplied by Selzer GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mitf+isoform+m+mitf+m/us07709454-1991-44-35?v=Selzer+GmbH
Average 90 stars, based on 1 article reviews
microphthalmia transcription factor - by Bioz Stars, 2026-08
90/100 stars
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c1000 touchtm thermal cycler  (Bio-Rad)
97
Bio-Rad c1000 touchtm thermal cycler
DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the <t>cAMP-CREB-MITF</t> cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.
C1000 Touchtm Thermal Cycler, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mitf+isoform+m+mitf+m/pmc06175185-81-8-12?v=Bio-Rad
Average 97 stars, based on 1 article reviews
c1000 touchtm thermal cycler - by Bioz Stars, 2026-08
97/100 stars
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live cell analysis instruments  (Sartorius AG)
99
Sartorius AG live cell analysis instruments
DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the <t>cAMP-CREB-MITF</t> cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.
Live Cell Analysis Instruments, supplied by Sartorius AG, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mitf+isoform+m+mitf+m/sartorius+ag___live-cell-analysis-instruments?v=Sartorius+AG
Average 99 stars, based on 1 article reviews
live cell analysis instruments - by Bioz Stars, 2026-08
99/100 stars
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Image Search Results


DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the cAMP-CREB-MITF cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.

Journal: Pigment cell & melanoma research

Article Title: MITF and UV responses in skin: from pigmentation to addiction

doi: 10.1111/pcmr.12726

Figure Lengend Snippet: DNA damage induced by UVR stabilizes p53, which subsequently promotes transcriptional activation of the pro-opiomelanocortin (POMC) gene. POMC is cleaved to yield multiple peptides, including α-MSH and the opioid β-endorphin. Stimulation of the MC1R signaling pathway by α-MSH ligand activates the cAMP-CREB-MITF cascade in melanocytes, resulting in the synthesis of melanin and eventual transfer of melanosomes to keratinocytes for protection against UV. β-endorphin has been shown to be involved in mood-related effects and analgesia dependency. In addition, salt inducible kinases (SIKs) phosphorylates the cAMP-regulated transcriptional co-activator (CRTC) family of proteins, thereby preventing translocation of CRTC to the nucleus and eventually leading to inhibition of transcriptional activation of MITF. UV absorption by 7-dyhrocholesterol (7-DHC) forms vitamin D3, an inactive form of vitamin D in keratinocytes.

Article Snippet: Among those, the M-isoform of MITF (MITF-M) is expressed almost exclusively in melanocytes ( Fuse, Yasumoto, Suzuki, Takahashi, & Shibahara, 1996 ), though it has also been detected in retinal pigment epithelium ( Bharti, Liu, Csermely, Bertuzzi, & Arnheiter, 2008 ; Masuda & Esumi, 2010 ) and likely in mouse olfactory bulb projection neurons (mitral cells and tufted cells) ( Ohba, Takeda, Yamamoto, & Shibahara, 2015 ).

Techniques: Activation Assay, Translocation Assay, Inhibition